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Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
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[Advances on terpenoids from genus Syringa].

Jia-Qi Gao1, Shun-Gang Jiao2, Jin-Yu Ma2

  • 1National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China School of Pharmacy, Jiangsu University Zhenjiang 212013, China.

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
|June 5, 2020
PubMed
Summary

Syringa plant terpenoids, particularly sesquiterpenoids, exhibit significant medicinal properties including cardioprotective and anti-inflammatory effects. This review highlights their potential for pharmaceutical development.

Keywords:
Syringachemical constituentspharmacological activitiesterpenoids

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Area of Science:

  • Phytochemistry
  • Pharmacology
  • Medicinal Botany

Background:

  • Syringa plants possess considerable ornamental, economic, and medicinal value.
  • Terpenoids, including iridoids, sesquiterpenoids, and triterpenoids, are key compounds found in Syringa species.
  • These terpenoids demonstrate a wide range of pharmacological activities, such as cardioprotective, neuroprotective, hypoglycemic, antiviral, antibacterial, anti-inflammatory, and antioxidant effects.

Purpose of the Study:

  • To review the phytochemical constituents of Syringa terpenoids.
  • To summarize the pharmacological activities of Syringa terpenoids.
  • To provide an overview for future research and development of Syringa plants.

Main Methods:

  • Literature review of phytochemical and pharmacological studies on Syringa terpenoids.
  • Analysis of reported chemical structures and biological activities.
  • Synthesis of current knowledge on Syringa plant compounds.

Main Results:

  • Syringa plants are rich sources of diverse terpenoids.
  • Sesquiterpenoids from Syringa plants show notable pharmacological effects, attracting significant research interest.
  • Identified activities include cardioprotective, neuroprotective, hypoglycemic, anti-influenza virus, antibacterial, anti-inflammatory, and antioxidant properties.

Conclusions:

  • Syringa terpenoids, especially sesquiterpenoids, hold substantial promise for therapeutic applications.
  • Further research into Syringa terpenoids can lead to the development of new pharmaceutical agents.
  • This review underscores the importance of exploring Syringa plants for novel drug discovery.