Developmental Outcomes of Children Born with Neonatal Abstinence Syndrome (NAS): A Scoping Review

Sandra Fucile1, Haley Gallant1, Anjali Patel2

  • 1Department of Pediatrics, Queen's University, Kingston, Ontario, Canada.

Insights

Neonatal Abstinence Syndrome (NAS) can impact child development, affecting cognitive, language, and motor skills. More research is needed to understand these developmental outcomes and improve interventions for affected infants.

Area of Science:

  • Developmental Pediatrics
  • Neonatal Health
  • Child Psychology

Background:

  • Neonatal Abstinence Syndrome (NAS) is a growing concern in neonatal care.
  • Infants with NAS exhibit a range of withdrawal symptoms impacting their early development.
  • Understanding long-term developmental trajectories is crucial for this vulnerable population.

Purpose of the Study:

  • To synthesize existing literature on the developmental outcomes of children diagnosed with NAS.
  • To identify key developmental domains affected in infants with NAS.
  • To highlight gaps in current research regarding NAS and child development.

Main Methods:

  • A scoping review methodology was employed, guided by the PRISMA framework.
  • A comprehensive literature search was conducted across major scientific databases (CINAHL, MEDLINE, EMBASE, Web of Science, PsycINFO).
  • Inclusion criteria focused on studies reporting developmental outcomes in children with NAS, with eight studies ultimately included after full-text screening.

Main Results:

  • Children with NAS may experience challenges in cognitive and language development.
  • School performance, social interactions, and motor skill development are potential areas of concern.
  • Inconsistent findings across studies complicate a definitive understanding of NAS developmental impacts.

Conclusions:

  • The developmental outcomes for infants with NAS are not yet firmly established due to conflicting research results.
  • Further longitudinal research across diverse age groups is essential.
  • Improved understanding will facilitate the development of targeted and effective intervention services for high-risk infants with NAS.
Abstract