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Updated: Dec 19, 2025
08:48
Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
Published on: February 16, 2022
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COVID-19: a conundrum to decipher.
V Deshmukh1, S C Tripathi, A Pandey
1Department of Anatomy, Biochemistry; All India Institute of Medical Sciences, Nagpur, Maharashtra, India. sctripathi@aiimsnagpur.edu.in.
Summary
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a global health crisis. This review summarizes SARS-CoV-2 epidemiology, clinical features, and management strategies for better control.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- The emergence of SARS-CoV-2 has led to the COVID-19 pandemic, a significant global health emergency.
- Early diagnosis and effective management of COVID-19 remain critical challenges.
Purpose of the Study:
- To provide a comprehensive review of the current understanding of SARS-CoV-2.
- To summarize updated information on SARS-CoV-2 epidemiology, pathogenesis, clinical manifestations, diagnosis, and prevention.
Main Methods:
- A comprehensive literature search was conducted across major databases including PubMed, Medline, Web of Science, Google Scholar, and WHO.
- Keywords used included "severe acute respiratory syndrome coronavirus", "2019-nCoV", "COVID-19", "SARS", "SARS-CoV-2", "Epidemiology", "Transmission", "Pathogenesis", and "Clinical Characteristics".
Main Results:
- As of April 2, 2020, COVID-19 cases exceeded 900,000 globally with over 47,000 deaths.
- COVID-19 incidence is predicted to be higher than previous coronavirus outbreaks like SARS-CoV and MERS-CoV.
- Clinical presentations range from asymptomatic to severe pneumonia, with common symptoms including fever, cough, and fatigue. Elderly individuals and those with comorbidities are at higher risk.
Conclusions:
- SARS-CoV-2 poses a substantial worldwide threat, impacting numerous countries.
- Further research into SARS-CoV-2 virology, epidemiology, and clinical management is crucial.
- Enhanced knowledge is essential for managing the current pandemic and preventing future outbreaks.
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