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Emergence of novel coronavirus and progress toward treatment and vaccine

Muhammad Muzamil Khan1,2, Amna Noor3, Asadullah Madni1

  • 1Department of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.

Reviews in Medical Virology
|June 5, 2020
PubMed

Insights

Scientists are exploring treatments and vaccines for SARS-CoV-2, the novel coronavirus causing a global pandemic. While no specific treatment is approved, ongoing clinical trials investigate existing drugs and new vaccine development.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • The emergence of SARS-CoV-2 in Wuhan, China, led to a global pandemic.
  • The novel coronavirus, SARS-CoV-2, is genetically linked to bat coronaviruses.
  • The World Health Organization (WHO) declared the outbreak a pandemic.

Purpose of the Study:

  • To summarize the global response to the SARS-CoV-2 pandemic.
  • To focus on the investigation of various treatment options for COVID-19.
  • To review ongoing clinical trials and vaccine development efforts.

Main Methods:

  • Review of scientific literature on SARS-CoV-2.
  • Analysis of ongoing clinical trials for COVID-19 treatments.
  • Examination of research progress in vaccine development.

Main Results:

  • No specific approved treatment currently exists for SARS-CoV-2.
  • Some existing antiviral and other drugs exhibit in vitro activity against the virus.
  • Numerous clinical trials are actively exploring potential treatments.

Conclusions:

  • The scientific community is actively engaged in combating the SARS-CoV-2 pandemic.
  • Research is focused on identifying effective treatments and developing vaccines.
  • Continued investigation and clinical trials are crucial for managing the pandemic.
Keywords:
SARS-CoV-2bat coronaviruschloroquineremdesivirvaccine

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