[Plasma and erythrocyte lipids in amyotrophic lateral sclerosis]

The authors studied the changes of lipids of the plasma and erythrocytes in 10 cases of amyotrophic lateral sclerosis and in 20 controls matched for age. In the plasma of patients with ALS increased levels were found of free cholesterol and triglycerides, with a decrease of lysophosphatidylcholine. The values of lipid fractions in erythrocyte membranes were not significantly different between these groups, with exception of increased level of total phospholipids (including phosphatidylethanolamine) and cholesterol.