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Malassezia Hepatic Abscess in a Neonate
Joseph B Cantey1, Steven D Dallas2, Francisco G Cigarroa3
1From the Departments of Pediatrics.
The Pediatric Infectious Disease Journal
|June 5, 2020
Summary
Malassezia fungi can infect neonates receiving intravenous lipids. This case highlights a potential Malassezia liver abscess linked to a misplaced umbilical venous catheter and lipid infusion.
Area of Science:
- Mycology
- Neonatal Medicine
- Infectious Diseases
Background:
- Malassezia species are fungi that depend on external lipids for growth.
- Neonates receiving intravenous lipid infusions are susceptible to disseminated Malassezia infections.
- Common presentations include fungemia or spread to the lungs and bones.
Observation:
- A neonate developed a presumed Malassezia liver abscess.
- The infection was associated with intravenous lipid infusion.
- A mispositioned umbilical venous catheter was identified as the likely route of administration.
Findings:
- This case suggests Malassezia liver abscess as a potential complication in neonates.
- The umbilical venous catheter may have facilitated direct fungal entry into the liver via lipid infusion.
- The findings expand the spectrum of Malassezia-related neonatal pathology.
Implications:
- Highlights the importance of catheter placement and lipid infusion practices in preventing fungal infections in neonates.
- Suggests considering Malassezia liver abscess in neonates with unexplained liver dysfunction and a history of lipid infusion.
- Underscores the need for vigilance regarding fungal infections in vulnerable neonatal populations.
