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Updated: Dec 19, 2025

How to Obtain Reliable Visual Event-related Potentials in Newborns
Published on: October 24, 2019
Newborn transient patterned hyperpigmentation and anophthalmia
Oscar F Chacón Camacho1,2, Rocío Arce-González1, Genaro Rodríguez Uribe3
1Departamento de Genética, Instituto de Oftalmología Conde de Valenciana, Mexico City, Mexico.
Background:
Transient pigmentary lines of the newborn are uncommon cutaneous lesions of unknown etiology. To date, only a few cases have been described.
Case Report:
A patient with a combination of transient pigmentary lines and ocular malformation is described. Molecular analysis of the SRY-box 2 (SOX2) and MIFT genes was conducted to rule out any monogenetic etiology.
Conclusions:
Worldwide, this is the eighth case of transient pigmentary lines of the newborn reported, and the first associated with anophthalmia. No mutations in the analyzed genes (SOX2 and MIFT) were identified. Therefore, somatic mutations could be responsible for this anomaly.
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