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Multistate Mumps Outbreak Originating from Asymptomatic Transmission at a Nebraska Wedding - Six States,

Matthew Donahue, Blake Hendrickson, Derek Julian

    MMWR. Morbidity and Mortality Weekly Report
    |June 5, 2020
    PubMed

    Insights

    A fully vaccinated individual caused a multistate mumps outbreak. This highlights the importance of measles-mumps-rubella (MMR) booster vaccinations to control mumps transmission.

    Area of Science:

    • Epidemiology
    • Public Health
    • Infectious Diseases

    Background:

    • Mumps outbreaks can occur even in highly vaccinated populations.
    • Asymptomatic transmission poses a significant challenge for disease control.

    Purpose of the Study:

    • To investigate a multistate mumps outbreak originating from a single, fully vaccinated, asymptomatic individual.
    • To understand the transmission dynamics of mumps in a vaccinated community.

    Main Methods:

    • Public health investigation involving contact tracing.
    • Epidemiologic analysis to identify transmission chains.
    • Community-wide measles-mumps-rubella (MMR) booster vaccination campaign.

    Main Results:

    • A single asymptomatic, fully vaccinated index patient exposed 30 wedding attendees to mumps.
    • The outbreak spread through secondary, tertiary, and quaternary cases, indicating sustained transmission.
    • A subsequent MMR booster vaccination campaign was implemented in the affected community.

    Conclusions:

    • Mumps transmission is possible even among individuals meeting Advisory Committee on Immunization Practices (ACIP) vaccination recommendations.
    • Asymptomatic carriers can be significant sources of infection.
    • Booster vaccination campaigns are crucial for controlling mumps outbreaks in communities with potential gaps in immunity.

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