Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Histogram01:05

Histogram

The histogram is a graphical representation in the x-y form of data distribution in a data set. The horizontal x-axis is labeled with what the data represents (for instance, distance from your home to school). The vertical y-axis is labeled either frequency or relative frequency (or percent frequency or probability).
A histogram graph consists of contiguous (adjoining) boxes. The heights of the bars correspond to frequency values. The graph will have the same shape with respective labels. The...
IR Spectrometers01:25

IR Spectrometers

There are two main infrared (IR) spectrophotometers: dispersive IR spectrometers and Fourier transform infrared (FTIR) spectrometers. In a dispersive IR spectrometer, a beam of infrared radiation produced by a hot wire is divided into two parallel equal-intensity beams using mirrors. One beam passes through the sample, while another is a reference beam. The beams then move through the monochromator, which separates the radiations into a continuous spectrum of different frequencies. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nefopam Misuse: A Cross-Sectional Study in France.

European journal of pain (London, England)·2025
Same author

[Management of image guidance doses delivered during radiotherapy].

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2021
Same author

Development and implementation in the Monte Carlo code PENELOPE of a new virtual source model for radiotherapy photon beams and portal image calculation.

Physics in medicine and biology·2016
Same author

Comparative validation of single-shot optical techniques for laparoscopic 3-D surface reconstruction.

IEEE transactions on medical imaging·2014
Same author

Denoising techniques combined to Monte Carlo simulations for the prediction of high-resolution portal images in radiotherapy treatment verification.

Physics in medicine and biology·2013
Same author

Effect of exercise on levels of cyclo-oxygenase mediators in exhaled breath condensate in elite athletes.

The Journal of sports medicine and physical fitness·2007

Related Experiment Video

Updated: Jul 24, 2026

Evaluation of the Spatial Distribution of γH2AX following Ionizing Radiation
09:28

Evaluation of the Spatial Distribution of γH2AX following Ionizing Radiation

Published on: August 7, 2010

13.0K

Validation of histogram-based virtual source models for different IGRT kV-imaging systems.

G Boissonnat1, H Chesneau1, E Barat1

  • 1CEA, LIST, System Modelling and Simulation Lab, Gif-sur-Yvette, F-91191, France.

Medical Physics
|June 5, 2020
PubMed
Summary

This study introduces a new method to model imaging doses in image-guided radiotherapy (IGRT). The virtual source model (VSM) accurately calculates patient-specific doses, improving treatment planning and reducing side effects.

Keywords:
IGRTMonte Carlo dose calculationvirtual source model

More Related Videos

A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells
12:49

A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells

Published on: September 28, 2019

13.2K
Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

13.1K

Related Experiment Videos

Last Updated: Jul 24, 2026

Evaluation of the Spatial Distribution of γH2AX following Ionizing Radiation
09:28

Evaluation of the Spatial Distribution of γH2AX following Ionizing Radiation

Published on: August 7, 2010

13.0K
A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells
12:49

A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells

Published on: September 28, 2019

13.2K
Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

13.1K

Area of Science:

  • Medical Physics
  • Radiotherapy
  • Radiation Dosimetry

Background:

  • Image-guided radiotherapy (IGRT) enhances tumor control but may increase late side effects due to additional imaging doses.
  • Accurate quantification of these imaging doses is crucial for integration into therapeutic workflows.
  • Current software limitations hinder patient-specific dose computation across diverse imaging systems.

Purpose of the Study:

  • To develop a common methodology for modeling four different kV-imaging systems used in radiotherapy.
  • To utilize a novel virtual source model (VSM) based on Monte Carlo calculations for dose estimation.
  • To enable precise, patient-specific 3D dose mapping for various kV-imaging procedures.

Main Methods:

  • Constructed simplified virtual source models (VSMs) summarizing phase-space files from initial Monte Carlo simulations.
  • Employed VSMs as photon generators for secondary Monte Carlo simulations to compute dose distributions.
  • Validated VSMs against standard Monte Carlo simulations and experimental measurements in homogeneous phantoms.

Main Results:

  • VSMs achieved dose calculation agreement within 1% compared to phase-space files within the imaging field-of-view.
  • A reduction in calculation time by at least a factor of 2.8 was observed using VSMs.
  • VSM-based calculations showed significantly lower statistical uncertainties for equivalent simulation times.

Conclusions:

  • Validated VSMs are ready for preclinical studies in heterogeneous or anthropomorphic phantoms.
  • The developed cross-system modeling methodology facilitates accurate patient-specific dose mapping in IGRT.
  • This approach supports improved integration of imaging doses into radiotherapy planning.