Silicone Oil-Associated Extensive Intraocular Ossification: A case report

Area of Science:

• Ophthalmology
• Pathology

Background:

• Intraocular ossification is a rare calcium deposition process.
• It is typically associated with ocular trauma, inflammation, tumors, or retinal detachment.
• This case presents extensive intraocular bone formation linked to silicone oil retention.

Observation:

• A patient with a history of ocular trauma and retinal detachment presented with a painful, blind eye.
• Examination revealed silicone oil emulsification, conjunctival congestion, and band keratopathy.
• Imaging and histopathology confirmed extensive ossification overlying the choroid.

Findings:

• Silicone oil retention in the eye is implicated as a potential accelerator of intraocular ossification.
• The case demonstrates a rare instance of significant bone formation within the eye.
• Histopathological analysis confirmed ossification overlying the choroid.

Implications:

• This finding suggests a potential complication of long-term silicone oil use in ophthalmology.
• Timely silicone oil removal may be crucial in preventing or managing intraocular ossification.
• Evisceration might be necessary for managing painful phthisis bulbi secondary to ossification.