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Updated: Dec 19, 2025

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Published on: September 22, 2023
The evolution of TIF: transoral incisionless fundoplication
1Matagorda Regional Medical Center, 600 Hospital Circle, Suite 201, Bay City, TX 77414, USA.
Abstract:
Transoral incisionless fundoplication (TIF) was introduced in 2006 as a concerted effort to produce a natural orifice procedure for reflux. Since that time, the device, as well as the procedure technique, has evolved. Significant research has been published during each stage of the evolution, and this has led to considerable confusion and a co-mingling of outcomes, which obscures the results of the current device and procedure. This report is intended to review the identified stages and literature associated with each stage to date and to review the current state of treatment outcomes.
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