Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.1K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.1K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.0K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.0K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

881
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
881

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chronic Ocular Surface Pain: A Missing Member of the Chronic Overlapping Pain Conditions?

Drugs·2026
Same author

Relevance of autoantibodies to carbonic anhydrase 6 (CA6), parotid secretory protein (PSP) and salivary gland protein 1 (SP1) to dry eye disease (DED).

BMJ open ophthalmology·2026
Same author

Serum Glutamate in Dry Eye Disease: Associations with Symptoms and Clinical Signs.

Diagnostics (Basel, Switzerland)·2026
Same author

Neuropsychological influences on visual photosensitivity and its treatment in traumatic brain injury.

BMJ open ophthalmology·2026
Same author

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry.

Arthritis care & research·2026
Same author

Artificial Intelligence for Diagnostic Guidance in Ocular Surface Disorders.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Dec 19, 2025

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
04:00

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Published on: August 2, 2024

3.0K

Ocular Surface Pain: A Narrative Review.

Divy Mehra1,2, Noah K Cohen2, Anat Galor3,4

  • 1Surgical Services, Miami Veterans Affairs Medical Center, Miami, FL, USA.

Ophthalmology and Therapy
|June 6, 2020
PubMed
Summary
This summary is machine-generated.

Ocular surface pain, affecting vision and healthcare costs, stems from corneal damage or nerve issues. Understanding neuropathic pain is key for diagnosing chronic dry eye and improving patient care.

Keywords:
Dry eyeNeuropathic painNociceptive painOcular painOcular surface pain

More Related Videos

Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.6K
Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.0K

Related Experiment Videos

Last Updated: Dec 19, 2025

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
04:00

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Published on: August 2, 2024

3.0K
Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.6K
Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.0K

Area of Science:

  • Ophthalmology and Neuroscience
  • Ocular surface disease research
  • Pain management in eye care

Background:

  • Ocular surface pain is a common reason for eye care visits, significantly impacting healthcare costs.
  • The cornea, densely innervated, is a major source of ocular pain, manifesting as nociceptive or neuropathic pain.
  • Current diagnostic tools and understanding of causative factors for ocular pain are insufficient in many clinics.

Purpose of the Study:

  • To provide an overview of ocular surface pain complaints.
  • To discuss the prevalence, physiological factors, and management strategies for ocular surface pain.
  • To highlight the differentiation between nociceptive and neuropathic ocular pain, especially in chronic dry eye.

Main Methods:

  • Literature review synthesizing current knowledge on ocular surface pain.
  • Exploration of neurobiological advances in differentiating pain types.
  • Analysis of diagnostic challenges and management approaches.

Main Results:

  • Ocular surface pain has significant prevalence and economic burden.
  • Distinguishing between nociceptive and neuropathic pain is crucial for accurate diagnosis.
  • Neuropathic pain mechanisms are increasingly implicated in chronic dry eye symptoms.

Conclusions:

  • A comprehensive understanding of ocular surface pain, including its neuropathic component, is vital for effective clinical practice.
  • Further research and improved diagnostic methods are needed to address the complexities of ocular pain.
  • Targeted management strategies are essential for patients suffering from ocular surface pain and dry eye disease.