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Subendocardial stress in pre-eclampsia

Tomio Tran1, Morteza Farasat1,2, Mori J Krantz1,2

  • 1Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
|June 6, 2020
PubMed

A primigravida 26-year-old woman who had developed pre-eclampsia with malignant hypertension at 30 weeks of gestation suffered acute myocardial infarction two days postpartum. Electrocardiogram demonstrated diffuse ST-segment depression suggestive of subendocardial ischemia. Echocardiography demonstrated focal asymmetric left ventricular hypertrophy, with a characteristic "basal septal bulge", and a left ventricular mid-cavitary gradient of 51 mmHg. Coronary angiography revealed normal coronary arteries and vascular flow. Peripartum acute myocardial infarction is rare and portends a high mortality. However, to date, only one case of acute myocardial infarction associated with asymmetric left ventricular hypertrophy and pre-eclampsia has been described in the literature.

Keywords:
basal septal bulgeleft ventricular outflow obstructionmyocardial infarctionpre-eclampsiapregnancysubendocardial ischemia

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