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The Effect of Aging on the Electrically Evoked Compound Action Potential
Bruna S Mussoi1, Carolyn J Brown2
1Speech Pathology and Audiology, Kent State University, Kent, Ohio.
Summary
Older cochlear implant (CI) users show reduced neural function, indicated by shallower electrically evoked compound action potential (eCAP) growth and higher thresholds, suggesting age-related neural loss.
Area of Science:
- Auditory Neuroscience
- Gerontology
- Biomedical Engineering
Background:
- Aging impairs speech-in-noise understanding, with potential peripheral auditory system contributions.
- Cochlear implants (CIs) allow direct auditory nerve stimulation, aiding investigation of age-related neural changes.
- Animal models suggest spiral ganglion cell loss impacts auditory nerve function and speech recognition.
Purpose of the Study:
- To investigate the impact of aging on electrically evoked compound action potential (eCAP) growth functions in CI users.
- To explore the relationship between eCAP growth functions and speech recognition in noise among different age groups.
Main Methods:
- Recruited 10 younger and 10 older adult CI recipients.
- Recorded eCAP amplitude-intensity functions from a mid-array electrode.
- Assessed speech recognition in noise using the Quick Speech-in-Noise (QuickSIN) test.
Main Results:
- Older CI users exhibited significantly shallower eCAP growth functions compared to younger users.
- Higher eCAP thresholds were observed in the older CI user group.
- eCAP growth functions did not correlate with speech recognition in noise performance.
Conclusions:
- Findings suggest poorer neural survival in older adults, leading to elevated eCAP thresholds and shallower eCAP growth.
- Results enhance understanding of age-related peripheral auditory system mechanisms in CI users.
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