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Angiostrongyliasis detected by next-generation sequencing in a ELISA-negative eosinophilic meningitis: A case report
Yueli Zou1, Hongzhi Guan2, Honglong Wu3
1Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Abstract:
Next-generation sequencing (NGS) is an emerging method with the potential of pan-pathogen screening. This study described a case of eosinophilic meningitis (EoM) with enzyme-linked immunosorbent assay (ELISA)-negative results for Angiostrongylus cantonensis (A. cantonensis), Trichinella spiralis and Paragonimus westermani and a positive identification of A. cantonensis by NGS in the cerebrospinal fluid.
