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Immunogenicity of cyclophosphamide-treated tumor cells
M Kawalec1, T Skórski, G Hoser
1Medical Center of Postgraduate Education, Department of Cytophysiology, Warsaw.
Archivum Immunologiae Et Therapiae Experimentalis
|January 1, 1988
Abstract:
The immunogenicity of cyclophosphamide-treated murine tumor cells was tested on syngeneic or semisyngeneic mice. The majority of mice immunized with modified Ehrlich carcinoma cells, L1210 leukemia cells or AA sarcoma cells survived after challenge with a lethal dose of unmodified tumor cells. Plasmacytomas RPC-5 and MOPC 104E were less immunogenic and L-1 sarcoma cells were not immunogenic.