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Infective endocarditis in the Netherlands: current epidemiological profile and mortality : An analysis based on
S El Kadi1, D M F van den Buijs1, T Meijers1
1location VU University Medical Centre, Department of Cardiology, Amsterdam UMC, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Summary
Infective endocarditis (IE) in the Netherlands showed a high rate of prosthetic valve involvement but relatively low mortality. Advanced imaging is widely used for diagnosis and follow-up in IE patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Infective endocarditis (IE) presents significant in-hospital and long-term mortality risks.
- Despite advancements, IE morbidity and mortality remain high.
- European guidelines highlight the crucial role of multi-modality imaging in IE diagnosis and management.
Purpose of the Study:
- To report mortality and adverse events in infective endocarditis (IE) patients.
- To characterize IE patient demographics and risk factors.
- To evaluate the current utilization of diagnostic imaging in IE.
Main Methods:
- Prospective observational cohort study design.
- Data collected from the EURO-ENDO registry.
- Inclusion of 139 IE patients from seven Dutch hospitals (April 2016 - April 2018).
Main Results:
- Prosthetic valve endocarditis (PVE) accounted for 32.4% of cases.
- In-hospital mortality was 14.4%, with one-year mortality at 21.6%.
- High utilization of echocardiography (97.8%), PET/CT (45.3%), and MSCT (42.4%) within days of IE suspicion.
Conclusions:
- The study observed a high prevalence of prosthetic valve endocarditis (PVE).
- Rapid and comprehensive use of advanced imaging modalities was noted.
- In-hospital and one-year mortality rates for IE in the Netherlands were relatively low, though selection bias is a limitation.
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