Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthetic Biology02:55

Synthetic Biology

5.4K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Harnessing Methyltransferase-Guided Targeting for Sequence-Specific Proximity Labeling of DNA.

Angewandte Chemie (International ed. in English)·2026
Same author

KRAS Can Bind to FTase Despite Disruption of the CAAX Binding Site.

Biochemistry·2026
Same author

FLIPs: Genetically encoded molecular biosensors for functional imaging of cell signaling by linear dichroism microscopy.

Science advances·2026
Same author

A Longitudinal 3D Live-Cell Imaging Platform to Uncover AAV Vector-Host Dynamics at Single-Cell Resolution.

International journal of molecular sciences·2026
Same author

Super-resolved Imaging of Molecular Interactions Using FRET-SOFI.

Nano letters·2025
Same author

Crystal structure analysis of oxygen-induced degradation occurring in rsCherry.

Acta crystallographica. Section F, Structural biology communications·2025

Related Experiment Video

Updated: Dec 19, 2025

Self-reporting Scaffolds for 3-Dimensional Cell Culture
14:49

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

13.6K

Genetically encoded biosensors based on innovative scaffolds.

Benjamien Moeyaert1, Peter Dedecker1

  • 1Laboratory for Nanobiology, Department of Chemistry, KU Leuven, Celestijnenlaan 200G, 3001 Heverlee, Belgium.

The International Journal of Biochemistry & Cell Biology
|June 7, 2020
PubMed
Summary

Genetically encoded biosensors enable visualization of cellular dynamics. Recent innovations focus on novel scaffolds for enhanced functionality and broader applications in living systems.

Keywords:
Cell imagingFluorescent proteinsGenetically encoded biosensorsProtein engineeringSelflabeling enzymes

More Related Videos

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
04:33

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

Published on: December 8, 2023

1.3K
Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
08:58

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

442

Related Experiment Videos

Last Updated: Dec 19, 2025

Self-reporting Scaffolds for 3-Dimensional Cell Culture
14:49

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

13.6K
Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
04:33

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

Published on: December 8, 2023

1.3K
Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
08:58

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

442

Area of Science:

  • Molecular Biology
  • Cell Biology
  • Biotechnology

Background:

  • Genetically encoded biosensors are crucial for real-time monitoring of cellular processes.
  • Advancements in biosensor technology are driven by the need for new analyte detection and improved sensor performance.
  • Existing biosensors face limitations in specificity, sensitivity, and applicability across diverse biological contexts.

Purpose of the Study:

  • To review recent breakthroughs in genetically encoded biosensor development.
  • To highlight novel and innovative scaffolds for future biosensor design.
  • To discuss the potential of advanced biosensors in visualizing cellular dynamics.

Main Methods:

  • Literature review of recent publications on genetically encoded biosensors.
  • Analysis of novel scaffold designs and their functional implications.
  • Synthesis of information on improved sensor characteristics and applications.

Main Results:

  • Identification of emerging trends in genetically encoded biosensor scaffolds.
  • Demonstration of enhanced functionality and robustness in newly developed sensors.
  • Examples of biosensors enabling visualization of diverse analytes and processes.

Conclusions:

  • Novel scaffolds are expanding the capabilities of genetically encoded biosensors.
  • Continued innovation in biosensor design promises new possibilities for live-cell imaging.
  • Genetically encoded biosensors will remain indispensable tools in biological research.