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Published on: October 2, 2019
Sleep surgery in syndromic and neurologically impaired children
Noor-E-Seher Ali1, Jennifer C Alyono1, Anisha R Kumar1
1Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, United States of America.
Insights
Surgery for obstructive sleep apnea (OSA) in children with comorbidities often requires additional interventions beyond adenotonsillectomy. Dissection of the pharynx (DISE) helps identify remaining obstruction sites for improved management.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Genetics and Rare Diseases
Background:
- Obstructive sleep apnea (OSA) is prevalent in children with syndromic or neurologic conditions.
- Management strategies for pediatric OSA with comorbidities require careful consideration.
Purpose of the Study:
- To evaluate surgical interventions for obstructive sleep apnea (OSA) in children with syndromic or neurologic comorbidities.
- To analyze the effectiveness of different surgical approaches and identify factors influencing outcomes.
Main Methods:
- Retrospective review of 375 pediatric OSA patients with various comorbidities.
- Analysis of surgical procedures, apnea-hypopnea index (AHI) changes, complications, and endoscopic findings.
Main Results:
- Adenoidectomy and tonsillectomy were the most frequent surgeries, significantly reducing AHI post-tonsillectomy.
- Tongue base and epiglottic retroflexion were common findings on DISE; lingual tonsillectomy showed limited AHI improvement.
- 228 patients underwent 297 surgical interventions.
Conclusions:
- Adenotonsillectomy is a primary treatment for syndromic/neurologically impaired children with OSA, especially with hypertrophy.
- Incomplete OSA resolution often necessitates further interventions.
- Dissection of the pharynx (DISE) is crucial for identifying residual obstruction and guiding subsequent management.
Purpose:
To examine surgery performed for obstructive sleep apnea (OSA) in children with syndromic or neurologic comorbidities.
Material And Methods:
Medical records of 375 children with OSA were retrospectively reviewed, including 142 patients with trisomy 21, 105 with cerebral palsy, 53 with muscular dystrophy, 32 with spinal muscular atrophy, 18 with mucopolysaccharidoses, 14 with achondroplasia, and 11 with Prader-Willi.
Outcome Measures:
Apnea-hypopnea index (AHI), complications, length of postoperative stay, and endoscopic findings.
Results:
228 patients received 297 surgical interventions, with the remainder undergoing observation or positive pressure ventilation. Adenoidectomy was the most common procedure performed (92.1% of patients), followed by tonsillectomy (91.6%). Average AHI decreased following tonsillectomy, from 12.4 to 5.7 (p = 0.002). The most common DISE finding was the tongue base causing epiglottic retroflexion. Lingual tonsillectomy also resulted in an insignificant decrease in the AHI.
Conclusions:
Adenotonsillectomy, when there is hypertrophy, remains the mainstay of management of syndromic and neurologically-impaired children with OSA. However, additional interventions are often required, due to incomplete resolution of the OSA. DISE is valuable in identifying remaining sites of obstruction and guiding future management.
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