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Employing an ICT-ESIPT strategy for ratiometric tracking of HClO based on sulfide oxidation reaction
Youming Shen1, Xin Liu1, Xiangyang Zhang1
1Hunan Provincial Key Laboratory of Water Treatment Functional Materials, Hunan Province Engineering Research Center of Electroplating Wastewater Reuse Technology, Hunan Province Cooperative Innovation Center for The Construction & Development of Dongting Lake Ecological Economic Zone, College of Chemistry and Materials Engineering, Hunan University of Arts and Science, Changde 415000, PR China.
Abstract:
Hypochlorous acid (HOCl) acts as crucial roles in pathologica processes and relevant diseases. Thus, it is meaningful to explore a reliable method for monitoring HClO in biosystem. In this work, a ratiometric fluorescent probe 2-(benzo[d]thiazol-2-yl)-4-(methylthio)phenol (BTMSP) has been constructed for HClO by adopting ICT-ESIPT strategy. The probe possessed itself red fluorescence due to the electron-donating capability of sulfur atom and showed remarkable blue fluorescence response to HClO by oxidizes the sulfur atom to a sulfoxide. The ratiometric probe exhibited highly specific, rapid response and excellent sensitivity toward HClO as well as a low detection limit (4.2 × 10-7 M). Moreover, the ratiometric probe showed well-separated dual emission (450/580), and a large pseudo Stokes shift (190 nm). In addition, the probe was used for the imaging of HClO with satisfying results.
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