Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dosage Regimen Designs: Nomograms and Tabulations01:23

Dosage Regimen Designs: Nomograms and Tabulations

104
Nomograms and tabulations are vital tools used by clinicians to design accurate and individualized dosage regimens. These instruments provide a straightforward method for adjusting dosages based on individual patient characteristics, including age, weight, and physiological condition. The foundation of a drug's nomogram is population pharmacokinetic data collected and analyzed using specific models. This data simplifies complex equations, presenting them diagrammatically or tabularly for easy...
104
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

461
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
461
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

421
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
421
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

1.2K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.2K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

734
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
734
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

791
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
791

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cavitary nodule caused by <i>Emergomyces orientalis</i> in a diabetic patient: a case report.

Frontiers in medicine·2026
Same author

Exceptional response to furmonertinib in lung adenocarcinoma harboring HER2 exon 20 insertion mutation: a case report.

Frontiers in oncology·2026
Same author

The impact of anemia on the risk of malignant central airway restenosis in lung squamous cell carcinoma patients post interventional bronchoscopy: a retrospective analysis.

Scientific reports·2025
Same author

Cryosurgery and Next-Generation Sequencing Unravel Talaromycosis Mimicking an Airway Tumor: A Case Report.

Infection and drug resistance·2025
Same author

From treatment to threat: the fatal impact of cumulative glucocorticoid dosage on outcomes in immunocompromised patients with community-acquired pneumonia.

Therapeutic advances in respiratory disease·2025
Same author

Systemic inflammation response index (SIRI)-based risk of pneumonia following successful PCI in STEMI patients.

Annals of medicine·2025

Related Experiment Video

Updated: Dec 19, 2025

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.5K

Nomogram to predict multidrug-resistant tuberculosis.

Saibin Wang1, Junwei Tu2

  • 1Department of Respiratory Medicine, Jinhua Municipal Central Hospital, Jinhua Hospital of Zhejiang University, No. 365, East Renmin Road, Jinhua, 321000, Zhejiang Province, China. saibinwang@hotmail.com.

Annals of Clinical Microbiology and Antimicrobials
|June 8, 2020
PubMed
Summary

A new nomogram can predict multidrug-resistant tuberculosis (MDR-TB) using five patient factors. This tool aids in identifying MDR-TB, especially in smear-negative cases, improving tuberculosis management.

Keywords:
InfectionMDR-TBPrediction

More Related Videos

Matrix-based DNA Extraction for Targeted Next-Generation Sequencing on Decontaminated Sputum Samples
06:07

Matrix-based DNA Extraction for Targeted Next-Generation Sequencing on Decontaminated Sputum Samples

Published on: June 6, 2025

823
Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
07:35

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Published on: April 25, 2014

13.1K

Related Experiment Videos

Last Updated: Dec 19, 2025

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.5K
Matrix-based DNA Extraction for Targeted Next-Generation Sequencing on Decontaminated Sputum Samples
06:07

Matrix-based DNA Extraction for Targeted Next-Generation Sequencing on Decontaminated Sputum Samples

Published on: June 6, 2025

823
Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
07:35

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Published on: April 25, 2014

13.1K

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Medical Diagnostics

Background:

  • Multidrug-resistant tuberculosis (MDR-TB) presents a growing global health challenge.
  • Accurate identification of MDR-TB is limited, particularly in smear-negative cases.
  • Effective TB management requires improved diagnostic tools.

Purpose of the Study:

  • To develop a predictive nomogram for multidrug-resistant tuberculosis (MDR-TB).
  • To identify key demographic and clinical factors associated with MDR-TB.
  • To enhance the early detection of MDR-TB.

Main Methods:

  • Development of a nomogram using demographic and clinical data from TB patients.
  • Application of LASSO regression for variable selection and predictor identification.
  • Multivariate logistic regression, AUC, calibration, and decision curve analysis (DCA) for model validation.

Main Results:

  • A nomogram incorporating five selected variables was constructed.
  • The nomogram demonstrated good predictive ability with an AUC of 0.759.
  • The model showed good calibration and clinical utility in predicting MDR-TB.

Conclusions:

  • A validated nomogram can predict MDR-TB based on five patient characteristics.
  • This tool is valuable for predicting MDR-TB in sputum-free or smear-negative individuals.
  • The nomogram offers a promising approach to improve MDR-TB diagnosis and management.