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Predictive value of early second trimester maternal serum cyclophilin A concentrations in women complicated with
Samettin Celik1, Canan Soyer Çalışkan1
1Department of Obstetrics and Gynecology , Education and Research Hospital , Samsun, Turkey.
Objective:
To investigate cyclophilin A in early second trimester of pregnancy before the onset of preeclampsia.
Methods:
In this prospective case-control study, 51 pregnant women whose serum were collected and stored and who developed preeclampsia in later follow-up and 41 pregnant women as control group were included.
Results:
Maternal serum cyclophilin A levels in the study group who developed preeclampsia in later follow-up were significantly higher than those of normal healthy pregnant women.
Conclusion:
Cyclophilin A may be a valuable predictor for pregnant women who subsequently develop preeclampsia in their pregnancies.
