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Subjective Cognitive Decline and Related Cognitive Deficits
Tong Si1, Guoqiang Xing2, Ying Han1,3,4
1Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Frontiers in Neurology
|June 9, 2020
Summary
Early detection of subjective cognitive decline (SCD), a preclinical stage of Alzheimer's disease (AD), is crucial for potential reversal of cognitive deficits. Research is advancing assessment tools, biomarkers, and interventions for SCD and TBI-related cognitive issues.
Area of Science:
- Neuroscience and Neurology
- Gerontology
- Cognitive Science
Background:
- Late-stage dementia, including Alzheimer's disease (AD), is irreversible with current treatments.
- Subjective cognitive decline (SCD) represents a preclinical stage of AD, characterized by self-reported cognitive difficulties.
- SCD is challenging to diagnose using objective measures, hindering timely intervention.
Purpose of the Study:
- To review recent advancements in subjective cognitive decline (SCD) research.
- To explore current assessment tools, biomarkers, neuroimaging techniques, and interventions for SCD.
- To discuss the prognosis of SCD and its potential connection to cognitive deficits induced by traumatic brain injury (TBI).
Main Methods:
- Comprehensive literature review of recent studies on subjective cognitive decline (SCD).
- Analysis of current diagnostic and assessment methodologies for SCD.
- Examination of neuroimaging, biomarker, and intervention strategies relevant to SCD and TBI.
Main Results:
- Significant research interest in the preclinical stage of Alzheimer's disease (AD), specifically subjective cognitive decline (SCD).
- Progress in developing assessment tools, biomarkers, and neuroimaging for SCD detection.
- Exploration of interventions and prognosis for SCD, with potential links to TBI-induced cognitive impairments.
Conclusions:
- Accurate diagnosis and early intervention during the SCD stage offer the best opportunity for reversing cognitive deficits.
- Continued research into SCD, its biomarkers, and interventions is vital for combating Alzheimer's disease.
- Understanding the relationship between SCD and TBI-induced cognitive deficits may reveal new therapeutic avenues.
Keywords:
Alzheimer's diseasediagnosisinterventionmild cognitive impairmentsubjective cognitive declinetraumatic brain injuryMore Related Videos
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