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Clinical interventions for severe and critical COVID-19: what are the options

Wei Yuan1, Sheng Liu2, Li Lu3

  • 1Department of Orthopedics, First Hospital of China Medical University Shenyang, China.

American Journal of Translational Research
|June 9, 2020
PubMed

Insights

This review summarizes clinical interventions for severe COVID-19. It aims to guide healthcare providers in treating critical coronavirus disease 2019 patients.

Area of Science:

  • Medical Research
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • The COVID-19 pandemic poses a significant global health threat.
  • Severe and critical cases of COVID-19 exhibit high mortality rates due to complications such as acute respiratory distress syndrome, acute respiratory failure, and multiple organ failure.
  • Existing research on COVID-19 characteristics is extensive, but treatment strategies for severe and critical cases remain limited.

Purpose of the Study:

  • To review and synthesize published evidence on clinical interventions for severe and critical COVID-19.
  • To provide an updated reference for clinicians managing severe and critical COVID-19 cases.

Main Methods:

  • A comprehensive literature review of published studies on clinical interventions for severe and critical COVID-19.
  • Systematic evaluation of evidence regarding treatment efficacy and safety.

Main Results:

  • The review identifies and analyzes various therapeutic approaches investigated for severe and critical COVID-19.
  • Key findings on the effectiveness and limitations of different interventions are presented.

Conclusions:

  • This review offers a consolidated overview of current treatment options for severe and critical COVID-19.
  • The findings aim to inform clinical decision-making and guide future research in managing severe coronavirus disease 2019.

Keywords:
COVID-19SARS-CoV-2interventionsevere pneumonia

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