Impact of exercise on hippocampal neurogenesis in hyperglycemic diabetes
Chae-Bin Lee1, Seung-Soo Baek1
1Department of Sport & Health Care, College of Art & Culture, Sangmyung University, Seoul, Korea.
Abstract:
Hyperglycemic diabetes is a chronic metabolic disorder characterized by high level of plasma glucose. Numerous studies have shown that hy-perglycemic diabetes leads to brain dysfunction including cognitive im-pairment and emotional disorders. This study evaluated the impact of exercise on brain dysfunction, hippocampal neurogenesis, and cogni-tive impairment in hyperglycemic diabetes. The present study suggests that exercise improves hyperglycemic control and prevents decline of cognition through increasing hippocampal neurogenesis. Understanding the mechanism of exercise for hippocampal neurogenesis can lead to the development of therapeutic strategies for metabolic disorders.
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