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Cytokines Induce Monkey Neural Stem Cell Differentiation through Notch Signaling

Min Wang1,2,3, Liming Yu3, Lu-Ying Zhu3

  • 1National Key Disciplines, Key Laboratory for Cellular Physiology of Ministry of Education, Department of Neurobiology, Shanxi Medical University, Taiyuan 030001, China.

Biomed Research International
|June 9, 2020
PubMed
Summary

Bone morphogenic protein 4 (BMP4) and other cytokines regulate monkey neural stem cell (NSC) proliferation and differentiation. BMP4/leukaemia inhibitory factor (LIF) promotes astrocyte differentiation, while retinoic acid (RA)/Forskolin induces neuronal differentiation via Notch signaling.

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