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Current perspectives on sex differences in tension-type headache
Stella Fuensalida-Novo1, Carmen Jiménez-Antona1, Elena Benito-González1
1Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos , Alcorcón, Spain.
Expert Review of Neurotherapeutics
|June 9, 2020
Summary
Gender significantly impacts pain perception, particularly in tension-type headache (TTH). Tailoring treatments for men and women with TTH, considering factors like sleep, depression, and stress, may improve outcomes.
Area of Science:
- Neurology
- Pain Medicine
- Psychology
Background:
- Growing evidence highlights gender-specific differences in pain perception and experience.
- Tension-type headache (TTH) presents unique challenges in management due to these observed gender disparities.
Purpose of the Study:
- To explore biological, psychological, emotional, and social factors contributing to gender differences in TTH.
- To inform clinicians about the importance of considering gender in TTH management strategies.
Main Methods:
- Review and synthesis of existing clinical and experimental evidence on gender differences in pain.
- Discussion of the interplay between TTH, emotional stress, sleep, and burden in different genders.
Main Results:
- Gender differences are evident in the presentation and experience of TTH.
- Interactions between TTH, stress, sleep, and burden vary significantly between men and women.
Conclusions:
- Multimodal treatment for TTH is recommended, with specific considerations for gender.
- Hypothesized targeted treatments: men with TTH may benefit from focusing on sleep and depression, while women may require attention to nociceptive mechanisms and stress factors.
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