Related Experiment Video

Updated: Dec 19, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

3.1K

COVID-19 and diabetes mellitus: implications for prognosis and clinical management

Thomas M Barber1,2

  • 1Division of Biomedical Sciences, Warwick Medical School, University of Warwick , Coventry, UK.

Expert Review of Endocrinology & Metabolism
|June 9, 2020
PubMed

Insights

The COVID-19 pandemic disproportionately affects individuals with diabetes mellitus (DM) due to impaired immunity. Effective management involves remote outpatient care and strict glycemic control to improve clinical outcomes.

Area of Science:

  • Infectious Diseases
  • Endocrinology
  • Public Health

Background:

  • COVID-19, a novel coronavirus, rapidly became a global pandemic originating in Wuhan, China.
  • Diabetes Mellitus (DM) is associated with compromised cellular and humoral immunity.
  • Emerging data indicate that comorbidities, particularly DM, are linked to increased COVID-19 severity, including hospitalization and ICU admission.

Purpose of the Study:

  • To review the impact of COVID-19 on patients with diabetes mellitus.
  • To outline key management principles for COVID-19 in individuals with DM.

Main Methods:

  • A PubMed search was conducted for published data on COVID-19, respiratory infections, and DM.
  • Analysis of emergent global data on COVID-19 clinical outcomes and associated comorbidities.

Main Results:

  • Diabetes Mellitus is a prominent comorbidity associated with severe COVID-19 outcomes.
  • Impaired immunity in DM patients contributes to increased susceptibility and severity of COVID-19.

Conclusions:

  • Management of COVID-19 in patients with DM requires focused outpatient care, utilizing remote strategies when necessary.
  • Maintaining optimal glycemic control is crucial for mitigating severe clinical outcomes in diabetic patients with COVID-19.
  • The COVID-19 pandemic offers opportunities to enhance patient care and societal values, shifting focus towards human-centric approaches.
Abstract

Keywords:
COVID-19diabetes mellitusglycemiaimmunityrespiratory infection

More Related Videos

Improving IV Insulin Administration in a Community Hospital12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.2K
A Zebrafish Model of Diabetes Mellitus and Metabolic Memory10:03

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Published on: February 28, 2013

26.4K

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.2K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
777
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.7K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
1.9K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.9K
Overview of Carbohydrate Metabolism01:19

Overview of Carbohydrate Metabolism

Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
2.9K