Two-Dimensional, High-Resolution Peripheral Refraction in Adults with Isomyopia and Anisomyopia

Area of Science:

• Ophthalmology
• Optometry
• Vision Science

Background:

• Myopia is a significant global health concern.
• Understanding refractive error distribution is crucial for myopia management.
• Peripheral refraction plays a role in myopia progression.

Purpose of the Study:

• To investigate two-dimensional peripheral refraction in fellow eyes of isomyopic and anisomyopic patients.
• To compare peripheral refraction patterns between isomyopic and anisomyopic individuals.

Main Methods:

• Recruited 68 young adults (25 isomyopes, 43 anisomyopes).
• Measured peripheral refraction (60° × 36°) using a Hartmann-Shack wavefront sensor.
• Analyzed refraction in 3x3 retinal zones for fellow eye comparison.

Main Results:

• Isomyopic fellow eyes showed no significant refraction differences in corresponding zones.
• Anisomyopic eyes displayed interocular differences (IODs) ranging from -1.40 to -2.46 D.
• Anisomyopia showed relative hyperopic shifts in nasal and temporal retina, varying with central IOD.

Conclusions:

• Isomyopic fellow eyes exhibit symmetrical peripheral refraction.
• Anisomyopic eyes demonstrate asymmetrical peripheral hyperopic shifts.
• Findings suggest asymmetrical peripheral refraction variations during myopia progression.