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Murine Model of Allergen Induced Asthma
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Immune Modulation in Asthma: Current Concepts and Future Strategies

Marek Lommatzsch1

  • 1Abteilung für Pneumologie/Interdisziplinäre Internistische Intensivstation, Medizinische Klinik I, Zentrum für Innere Medizin, Universitätsmedizin Rostock, Rostock, Germany, marek.lommatzsch@med.uni-rostock.de.

Respiration; International Review of Thoracic Diseases
|June 9, 2020
PubMed

Asthma treatment concepts have profoundly changed over the last 20 years, from standard therapeutic regimens for all patients with asthma towards individually tailored interventions targeting treatable traits ("precision medicine"). A precise and highly effective immune modulation with minimal adverse effects plays a central role in this new concept. Recently, there have been major advances in the treatment of asthma with immune-modulatory compounds. One example is the approval of several highly potent biologics for the treatment of severe asthma. New immune-modulatory strategies are expected to enter clinical practice in the future; these innovations will be especially important for patients with treatment-resistant asthma.

Keywords:
Allergen immunotherapyAsthmaImmune modulationOral corticosteroids

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