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Related Concept Videos

Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

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Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
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Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
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Standard Precaution01:26

Standard Precaution

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Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
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Personal Protective Equipment01:20

Personal Protective Equipment

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Personal protective equipment (PPE) is unique clothing or equipment worn by an employee to minimize or prevent exposure to infectious agents. PPE creates a barrier between the employee and the infectious materials. PPE must be readily available in the patient care area. PPE includes gloves, gowns and aprons, masks and respirators, goggles, face shields, shoes, and headcovers:
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PPE Use in Healthcare Settings II: Doffing01:10

PPE Use in Healthcare Settings II: Doffing

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The sequence of removing or doffing PPE starts with the gloves, as they are the most contaminated. Next is removal of the face shield or goggles, as they would interfere with removing other PPE. Then remove the gown, followed by the mask or respirator. Perform hand hygiene between steps if hands become contaminated and immediately after removing all PPE. Generally, the outside front and sleeves of the isolation gown, the goggles or the mask, the respirator, and the face shield are contaminated.
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PPE Use in Healthcare Settings I: Donning01:22

PPE Use in Healthcare Settings I: Donning

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Donning PPE must be completed before contact with the patient. This process protects from infectious agents. The sequence and action included in each donning are critical, and the steps must be systematic to avoid exposure to pathogens. The institutional policy also needs to be followed while donning PPE. The pre-donning preparations are gathering equipment, inspecting the PPE equipment for tears, holes, or damage, removing jewelry, removing any garments below the elbows, and tying the hair...
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Related Experiment Video

Updated: Dec 19, 2025

Author Spotlight: Rabies-Specific Antibody Isotypes Detection in Sera or Cerebral Spinal Fluid Using an IFA Test
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COVID-19: Time for Post-Exposure Prophylaxis?

Ivan Gentile1,2, Alberto Enrico Maraolo1, Prisco Piscitelli2,3

  • 1Department of Clinical Medicine and Surgery-Section of Infectious Diseases, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy.

International Journal of Environmental Research and Public Health
|June 10, 2020
PubMed
Summary
This summary is machine-generated.

Post-exposure chemoprophylaxis (PEP) with antiviral drugs may help prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection after unprotected contact. This strategy offers a tailored intervention to mitigate COVID-19 spread.

Keywords:
COVID-19healthcarepost-exposureprophylaxis

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Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • The novel coronavirus SARS-CoV-2 causes COVID-19, presenting a significant global healthcare challenge.
  • High contagiousness and hospital capacity saturation are major concerns.
  • Non-pharmaceutical interventions are vital but may require supplementary individual-level strategies.

Purpose of the Study:

  • To explore the potential of post-exposure chemoprophylaxis (PEP) as an intervention against SARS-CoV-2.
  • To evaluate the feasibility of using antiviral drugs after potential exposure to COVID-19.

Main Methods:

  • Review of PEP strategies for other respiratory viruses, including influenza and MERS-CoV.
  • Examination of initial experiences with hydroxychloroquine for COVID-19 prevention.
  • Discussion of the application of PEP in high-risk contact scenarios.

Main Results:

  • PEP has been successfully implemented for other coronaviruses like MERS-CoV.
  • Antiviral combinations like lopinavir-ritonavir plus ribavirin were used for MERS-CoV PEP.
  • Early findings suggest hydroxychloroquine may be promising for COVID-19 prevention.

Conclusions:

  • Post-exposure chemoprophylaxis (PEP) is a viable strategy to consider for individuals exposed to SARS-CoV-2.
  • PEP can complement existing public health measures to control the COVID-19 pandemic.
  • Antiviral treatments following exposure may reduce the transmission of SARS-CoV-2.