Choroidal nevus and polypoidal vasculopathy: case series.

Area of Science:

• Ophthalmology
• Medical Imaging

Background:

• Investigating the association between choroidal nevus and polypoidal choroidal vasculopathy (PCV).
• Reporting on three isolated cases presenting with subretinal exudation and choroidal nevus.

Observation:

• Patients underwent comprehensive ophthalmic evaluations including slit lamp biomicroscopy, fundus photography, fluorescein angiography (FA), indocyanine green angiography (ICG), B-scan ultrasound, and spectral-domain optical coherence tomography (SD-OCT).
• All three patients exhibited classic features of choroidal neovascularization consistent with PCV.
• Substantial response to intravitreous antiangiogenic agents was observed in all cases.

Findings:

• Diagnostic imaging (OCT, FA, ICG angiography, FAF) revealed consistent findings across all three patients.
• A distinct clinical pattern linking choroidal nevus and PCV was identified.

Implications:

• The identified clinical pattern of co-occurring choroidal nevus and PCV can be diagnosed early.
• Advanced imaging modalities like FA, ICG, and OCT are crucial for early and accurate diagnosis.