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Updated: Dec 18, 2025

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution
04:14

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution

Published on: April 16, 2019

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Combined alcoholic and non-alcoholic steatohepatitis

Line Carolle Ntandja Wandji1,2,3, Viviane Gnemmi4, Philippe Mathurin1,2,3

  • 1Service des maladies de l'appareil digestif, Hôpital Huriez, Rue Polonowski, 59037 Lille Cedex, France.

JHEP Reports : Innovation in Hepatology
|June 10, 2020
PubMed

Keywords:
ACC, acetyl-CoA carboxylaseALDALD, alcohol-related liver diseaseASHASH, alcohol-related steatohepatitisASK-1, apoptosis signal-regulating kinase 1AlcoholBMI, body mass indexCLD, chronic liver diseaseCPT, carnitine palmitoyltransferaseDNL, de novo lipogenesisEASL, European Association for the Study of the LiverER, endoplasmic reticulumFXR, farnesoid X receptorHCC, hepatocellular carcinomaHSD17B13, hydroxysteroid 17-beta dehydrogenase 13IL, interleukinLPS, lipopolysaccharideMBOAT7, membrane bound O-acyl transferase 7MELD, model for end-stage liver diseaseNAFLDNAFLD, non-alcoholic fatty liver diseaseNASHNASH, non-alcoholic steatohepatitisOR, odds ratioPAMP, pathogen-associated molecular patternPI3K, phosphatidylinositol-3-kinasePIP3, phosphatidylinositol 3,4,5-triphosphatePNPLA3, palatin-like phospholipase domain-containing 3PRKCE, protein kinase C EpsilonROS, reactive oxygen speciesSREBP-1c, sterol regulatory element binding protein-1cTLR, Toll-like receptorTM6SF2, transmembrane 6 superfamily member 2TNF-α, tumour necrosis factor-αWHO, World Health Organizationdiabetesmetabolic syndromeobesity

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