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[COVID-19 associated severe psychotic relapse]
David Hvidtfelt Hansen1, Lone Baandrup, Ida Hageman
1david.hvidtfelt.hansen@regionh.dk.
Ugeskrift for Laeger
|June 10, 2020
Summary
A patient with schizophrenia experienced a severe psychotic relapse after contracting SARS-CoV-2. This case report explores a potential link between the virus and neuroinflammation triggering psychosis.
Area of Science:
- Neuroscience
- Infectious Diseases
- Psychiatry
Background:
- A 42-year-old patient with a history of catatonic schizophrenia, untreated for four years, presented with pneumonia.
- The patient tested positive for SARS-CoV-2, the virus causing COVID-19.
Observation:
- Following initial treatment and discharge, the patient was readmitted seven days later with severe psychosis.
- This clinical course raises questions about the potential impact of SARS-CoV-2 infection on individuals with pre-existing mental health conditions.
Findings:
- The case report hypothesizes that a neuroinflammatory response secondary to SARS-CoV-2 infection may have triggered the psychotic relapse.
- This suggests a potential connection between viral infections and the exacerbation of psychiatric symptoms.
Implications:
- Further research is warranted to investigate the neuroinflammatory mechanisms by which SARS-CoV-2 might influence psychiatric conditions.
- Understanding this link could inform clinical management strategies for patients with both infectious diseases and severe mental illness.
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