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Updated: Dec 18, 2025
Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
Cell-laden alginate hydrogels for the treatment of diabetes
Lukin Izeia1,2, Tatiane Eufrasio-da-Silva3, Alireza Dolatshahi-Pirouz3,4
1NanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country UPV/EHU , Vitoria-Gasteiz, Spain.
Introduction:
Diabetes mellitus is an ever-increasing medical condition that currently suffers 1 of 11 adults who may have lifelong commitment with insulin injections. Cell-laden hydrogels releasing insulin may provide the ultimate means of correcting diabetes. Here, we provide insights of this cell-based approach including latest preclinical and clinical progress both from academia and industry.
Area Covered:
The present article focuses on reviewing latest advances in cell-laden hydrogels both from the technological and biological perspective. The most relevant clinical results including clinical trials are also discussed.
Expert Opinion:
Current progress in technological issues (stem cells, devices, biomaterials) have contributed cell encapsulation science to have a very relevant progress in the field of diabetes treatment.
