Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Theories of Dissolution: Diffusion Layer Model

Theories of Dissolution: Diffusion Layer Model

Dissolution, the process by which drug particles dissolve in a solvent, is explained by the diffusion layer model, a theoretical framework that simulates the absorption of oral drugs and allows us to analyze experimental data.
This process starts with a thin layer, saturated with the drug, forming at the interface between the solid and liquid. The solute then diffuses from this layer into the main solution. The Noyes-Whitney equation suggests that the rate of dissolution relies on the diffusion...

Common Ion Effect

Common Ion Effect

Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A staging Monte Carlo algorithm for sampling off-diagonal density matrix elements via open-chain path integrals.

The Journal of chemical physics·2026

Same author

MXtalTools: A Toolkit for Machine Learning on Molecular Crystals.

Journal of chemical information and modeling·2026

Same author

Automated Machine Learning Pipeline: Large Language Models-Assisted Automated Data set Generation for Training Machine-Learned Interatomic Potentials.

Journal of chemical theory and computation·2025

Same author

Machine learning-accelerated path integral molecular dynamics simulations of reactive organic electrolytes.

The Journal of chemical physics·2025

Same author

3D conformation and crystal interaction insights into drug development challenges for HCV drug analogues via molecular simulations.

Communications chemistry·2025

Same author

Solute Tempered Adiabatic Free Energy Dynamics for Enhancing Conformational Space Sampling.

Journal of chemical theory and computation·2025

Same journal

Linking Local Water Electrostatic Potentials to Measured Hydrogen Evolution Onset in Aqueous Electrolytes.

The journal of physical chemistry letters·2026

Same journal

Microsolvation Redirects Electron-Induced Chemistry in Nucleobases.

The journal of physical chemistry letters·2026

Same journal

Interfacial Microenvironment Effects on the Mechanism of Photocatalytic Methanol Conversion for Hydrogen Evolution.

The journal of physical chemistry letters·2026

Same journal

Noncovalent Interactions in Protein-Ti Binding: Titan Bonds at Work.

The journal of physical chemistry letters·2026

Same journal

Partial Phase Remixing of Segregated Mixed Halide Perovskite Nanocrystals Induced by an Instant Change in an External Electric Field.

The journal of physical chemistry letters·2026

Same journal

Pressure-Driven Dissociation of a Kr Clathrate in the Presence of Colloids.

The journal of physical chemistry letters·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 18, 2025

Author Spotlight: A Rapid, Microwave-Assisted Hydrothermal Synthesis Of Nickel Hydroxide Nanosheets

Author Spotlight: A Rapid, Microwave-Assisted Hydrothermal Synthesis Of Nickel Hydroxide Nanosheets

Published on: August 18, 2023

Water Layering Affects Hydroxide Diffusion in Functionalized Nanoconfined Environments.

Tamar Zelovich¹, Mark E Tuckerman^1,2,3

¹Department of Chemistry, New York University (NYU), New York, New York 10003, United States.

The Journal of Physical Chemistry Letters

|June 10, 2020

Summary

This summary is machine-generated.

Hydroxide ions in anion exchange membranes exhibit unique solvation patterns in different water layers. These distinct structures influence ion diffusion, offering insights for designing better membranes with enhanced conductivity.

More Related Videos

Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance

Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance

Published on: September 5, 2018

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Published on: April 12, 2019

Related Experiment Videos

Last Updated: Dec 18, 2025

Author Spotlight: A Rapid, Microwave-Assisted Hydrothermal Synthesis Of Nickel Hydroxide Nanosheets

Author Spotlight: A Rapid, Microwave-Assisted Hydrothermal Synthesis Of Nickel Hydroxide Nanosheets

Published on: August 18, 2023

Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance

Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance

Published on: September 5, 2018

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Published on: April 12, 2019

Area of Science:

Physical Chemistry
Materials Science
Computational Chemistry

Background:

Anion exchange membranes (AEMs) are crucial for electrochemical applications.
Understanding ion transport in nanoconfined environments is key to AEM performance.
Water layers within AEMs significantly influence ion mobility.

Purpose of the Study:

To elucidate solvation patterns of hydroxide ions in distinct water layers within nanoconfined environments.
To investigate the diffusion mechanisms of hydroxide ions across these layers.
To correlate solvation structures with hydroxide ion transport rates.

Main Methods:

Utilizing fully atomistic *ab initio* molecular dynamics simulations.
Analyzing solvation structures and coordination patterns of hydroxide ions.
Characterizing diffusion mechanisms at the molecular level.

Main Results:

Identified unique solvation patterns for hydroxide ions in each water layer.
Observed distinct coordination complexes of hydroxide ions differing among layers.
Demonstrated that solvation structures directly impact hydroxide ion diffusion rates.

Conclusions:

Different water layers within AEMs exhibit varying abilities to promote or hinder hydroxide diffusion.
Solvation complex structures are critical determinants of hydroxide transport.
Findings provide a molecular-level understanding to guide the engineering of AEMs with improved hydroxide conductivity.