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Nonsteroidal antiinflammatory agents. XVIII - Stereomeric optically active halogenophenyl-biphenylyl-hydroxypropionic
L Varoli1, S Burnelli, A Guarnieri
1Departimento di Scienze Farmaceutiche Università di Bologna, Italy.
Il Farmaco; Edizione Scientifica
|November 1, 1988
Abstract:
The optically active stereomers of some 3-(fluoro-, chloro-, bromophenyl)-2-biphenylyl-3-hydroxypropionic acids were prepared and tested for antiinflammatory activity. Surprisingly, the four bromo-isomers were the most active ones, particularly in the threo configuration.