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Hard flaccid syndrome: state of current knowledge
Maher Abdessater1, Anthony Kanbar2, William Akakpo1
1Department of urology, APHP -La Pitié-Salpêtrière University Hospital, 47-83 Boulevard de l'hopital, 75013 Paris, France.
Basic and Clinical Andrology
|June 11, 2020
Summary
Hard-flaccid syndrome, a poorly understood male sexual dysfunction, is characterized by a semi-rigid flaccid penis and loss of erectile rigidity. A multimodal treatment approach shows promise for managing this condition.
Area of Science:
- Urology
- Andrology
- Sexual Medicine
Background:
- Hard-flaccid syndrome is an emerging male sexual dysfunction characterized by poor understanding and definition.
- Information primarily originates from online forums, highlighting a need for clinical review.
Purpose of the Study:
- To review current knowledge on hard-flaccid syndrome.
- To detail its clinical presentation, diagnosis, pathophysiology, and treatment.
Main Methods:
- A literature review was conducted using MEDLINE, CENTRAL, PASCAL, and Google Scholar.
- Search terms included 'hard,' 'flaccid,' and 'syndrome,' identifying 7 eligible articles published between 2018 and February 2019.
Main Results:
- The condition is acquired, chronic, and painful, presenting with a semi-rigid flaccid penis, sensory changes, urinary symptoms, erectile dysfunction, and psychological distress.
- It predominantly affects young men (20s-30s) following penile trauma, involving neurovascular damage.
- Diagnosis relies on history; imaging and blood tests are normal. Multimodal treatment is most beneficial.
Conclusions:
- Hard-flaccid syndrome is underrecognized and ill-defined in clinical practice.
- A multimodal treatment strategy appears most effective currently.
- Further high-quality studies are needed to elucidate pathophysiology and refine treatments.

