Polyarteritis nodosa with genital necrosis
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Updated: Dec 18, 2025

Anti-Nuclear Antibody Screening Using HEp-2 Cells
Published on: June 23, 2014
Paula Grinstein1, Lopez Silva Maximiliano2,3, Yirula Lucas4
1Urology Resident, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina.
Abstract:
Polyarteritis nodosa (PAN) is a multisystemic disease that is characterized by the presence of necrotizing vasculitis of small and medium-sized blood vessels. Genital compromise is rare. Our patient presented a systemic disease associated to genital signs (penis and scrotum skin necrosis). A bilateral testicular and glans biopsy was performed and with PAN diagnosis, immunosuppressives treatment was realised for 6 weeks, with favorable progress.
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