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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Neuroimaging in tuberous sclerosis complex.

Camilla Russo^1,2, Anna Nastro¹, Domenico Cicala¹

¹Department of Pediatric Neurosciences, Pediatric Neuroradiology Unit, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery

|June 11, 2020

Summary

This summary is machine-generated.

Tuberous sclerosis complex (TSC) is a genetic disorder impacting multiple systems. Neuroimaging, particularly MRI, is vital for diagnosing and understanding neurological issues in TSC patients.

Keywords:

Autism Central nervous system Epilepsy Magnetic resonance imaging Sub-ependymal giant cell astrocytoma Tuberous sclerosis complex

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Area of Science:

Genetics and Neurology
Rare Disease Research

Background:

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutations in TSC1 or TSC2 genes.
Neurological manifestations occur in 95% of TSC cases, leading to significant morbidity and mortality.

Purpose of the Study:

To review current knowledge on brain imaging in TSC.
To highlight the role of advanced neuroimaging techniques in understanding TSC pathophysiology.
To provide an overview of future neuroimaging applications for TSC.

Main Methods:

Review of existing literature on TSC neuroimaging.
Description of conventional imaging findings.
Discussion of advanced neuroimaging techniques.

Main Results:

Computed tomography (CT) is a first-line emergency investigation.
Magnetic resonance imaging (MRI) is the gold standard for CNS assessment in TSC.
Advanced MRI techniques offer new insights into TSC pathophysiology.

Conclusions:

Neuroimaging is essential for TSC diagnosis, monitoring, and management.
Advanced techniques enhance understanding of TSC brain alterations.
Future neuroimaging research holds promise for improved TSC patient care.