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[The effect of netilmicin on gram negative rods isolated in the Konya region]
A Z Sengil1, H Ozenci, M Altindiş
1Selçuk Universitesi, Tip Fakültesi, Mikrobiyoloji Anabilim Dali, Konya.
Mikrobiyoloji Bulteni
|January 1, 1988
Abstract:
Netilmicin, was tested for the effect against 276 isolates of gram negative bacteria, before had used in Konya region. 15.9% of the isolates were resistant and 84.1% were sensitive to netilmicin. The effects of Netilmicin and gentamicin for 50 Pseudomonas isolates were compared. The other aminoglycosides also were tested against isolates of the bacterium, amikacin was the most active one.
Insights
Netilmicin shows high sensitivity against Gram-negative bacteria in the Konya region. Amikacin demonstrated the most potent activity among tested aminoglycosides against Pseudomonas isolates.
Area of Science:
- Microbiology
- Infectious Diseases
- Pharmacology
Context:
- The increasing prevalence of antibiotic resistance necessitates evaluating the efficacy of existing antimicrobial agents.
- Gram-negative bacteria pose a significant threat in healthcare settings, particularly in the Konya region.
- Understanding regional antibiotic susceptibility patterns is crucial for effective treatment strategies.
Purpose:
- To assess the in vitro activity of netilmicin against a collection of Gram-negative bacterial isolates from the Konya region.
- To compare the efficacy of netilmicin with gentamicin against Pseudomonas isolates.
- To determine the spectrum of activity of various aminoglycoside antibiotics against Gram-negative bacteria.
Summary:
- Netilmicin was tested against 276 Gram-negative bacterial isolates, revealing an 84.1% sensitivity rate.
- A comparative analysis of netilmicin and gentamicin against 50 Pseudomonas isolates was conducted.
- Amikacin emerged as the most active aminoglycoside against the tested bacterial isolates.
Impact:
- This study provides valuable data on netilmicin's effectiveness in the Konya region, informing clinical prescribing practices.
- The findings highlight amikacin as a potentially superior alternative for treating Pseudomonas infections in this geographical area.
- The research contributes to the broader understanding of aminoglycoside resistance and efficacy in Gram-negative pathogens.