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Updated: Dec 18, 2025

Basics of Multivariate Analysis in Neuroimaging Data
Published on: July 24, 2010
Multivariate Outliers: A Conceptual and Practical Overview for the Nurse and Health Researcher
Maher M El-Masri1, Fabrice I Mowbray2, Susan M Fox-Wasylyshyn3
1College of Nursing, Wayne State University, Detroit, MI, USA.
Abstract:
The presence of statistical outliers is a shared concern in research. If ignored or improperly handled, outliers have the potential to distort parameter estimates and possibly compromise the validity of research findings. The purpose of this paper is to provide a conceptual and practical overview of multivariate outliers with a focus on common techniques used to identify and manage multivariate outliers. Specifically, this paper discusses the use of Mahalanobis distance and residual statistics as common multivariate outlier identification techniques. It also discusses the use of leverage and Cook's distance as two common techniques to determine the influence that multivariate outliers may have on statistical models. Finally, this paper discusses techniques that are commonly used to handle influential multivariate outlier cases.
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