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Updated: Dec 18, 2025

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
Myocardial ischaemia and valve insufficiency caused by a dysplastic aortic valve cusp: a previously unreported unique
Sharmeen Samuel1, Preeta Dhanantwari1, David B Meyer1
1Section of Pediatric Cardiology, Departments of Pediatrics and Cardiovascular Surgery, Cohen's Children's Hospital, Northwell Health, Donald and Barbara Zucker School of Medicine at Hofstra University, New York, NY, USA.
Abstract:
Isolated aortic regurgitation and myocardial infarction are a rare congenital defect among neonatal patients. We present a case of a neonate with an unusual aortic valve morphology causing both regurgitation and obstruction of the left coronary artery ostium. Despite both non-invasive and invasive imaging modalities, accurate diagnosis of the valve morphology was only determined by direct visualisation at the time of surgical repair. To the knowledge of authors, this particular aortic valve morphology in neonatal population has not been previously reported in the literature.
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