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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
249
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

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The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
282
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

548
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
548
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

216
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
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High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
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COVID-19 Presenting as Acute Limb Ischaemia.

Parminder Kaur1, Sahitya Posimreddy1, Balraj Singh2

  • 1Cardiology, Saint Joseph's University Medical Center, Paterson, New Jersey, USA.

European Journal of Case Reports in Internal Medicine
|June 12, 2020
PubMed
Summary

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause arterial thrombosis, leading to acute limb ischemia. This case highlights the importance of suspecting vascular emergencies in COVID-19 patients.

Keywords:
COVID-19arterial thrombosissevere acute respiratory syndrome coronavirus 2

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Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Vascular Surgery

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has significant health and economic impacts.
  • While COVID-19 complications include coagulation issues, literature on thrombosis is limited.
  • Disseminated coagulation and thrombosis are known complications of COVID-19.

Purpose of the Study:

  • To report an unusual case of arterial thrombosis in a COVID-19 patient.
  • To add to the limited literature on COVID-19-related vascular manifestations.
  • To emphasize the need for vigilance regarding acute limb ischemia in COVID-19.

Main Methods:

  • Case report of a 43-year-old male with diabetes and hypertension.
  • Presentation with dyspnea and acute right leg pain.
  • Diagnosis of acute limb ischemia and diabetic ketoacidosis.

Main Results:

  • The patient presented with symptoms indicative of acute limb ischemia.
  • Diabetic ketoacidosis was also diagnosed concurrently.
  • The case demonstrates a link between COVID-19 and arterial thrombosis.

Conclusions:

  • Acute limb ischemia, a form of arterial thrombosis, can be a manifestation of COVID-19.
  • A high index of suspicion for acute limb ischemia is crucial in COVID-19 patients.
  • Acute limb ischemia is a vascular emergency requiring prompt recognition and management.