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Kidney Health for Everyone Everywhere - From Prevention to Detection and Equitable Access to Care
Philip Kam-Tao Li1, Guillermo Garcia-Garcia2, Siu-Fai Lui3
1Department of Medicine and Therapeutics, Carol and Richard Yu PD Research Centre, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China.
Insights
Chronic kidney disease (CKD) is a growing global health crisis. Preventive measures, including risk factor modification and political action, are crucial to reduce the burden of kidney disease.
Area of Science:
- Nephrology
- Public Health
- Preventive Medicine
Background:
- Chronic kidney disease (CKD) presents a significant and escalating global health challenge, projected to be the fifth leading cause of years of life lost by 2040.
- CKD imposes a substantial economic burden, with dialysis and transplantation accounting for up to 3% of healthcare budgets in high-income nations.
- Despite its severity, the onset and progression of CKD are largely preventable through targeted interventions.
Discussion:
- Primary prevention involves modifying risk factors, addressing kidney abnormalities, and mitigating exposure to environmental hazards and nephrotoxins.
- Secondary prevention focuses on blood pressure and glycemic control in individuals with existing kidney disease.
- Tertiary prevention in advanced CKD patients aims to manage comorbidities like uremia and cardiovascular disease to delay or avoid renal replacement therapy.
Key Insights:
- A multi-faceted preventive approach encompassing primary, secondary, and tertiary measures is crucial for combating CKD.
- Effective CKD prevention requires a coordinated effort involving public awareness, professional education, and robust political will.
- Existing national non-communicable disease strategies often lack specific policies for CKD education, screening, and management.
Outlook:
- There is an urgent need for increased awareness regarding CKD prevention among the general public, healthcare professionals, and policymakers.
- Developing and implementing targeted national policies for CKD screening, management, and treatment is essential.
- Integrating comprehensive preventive strategies into healthcare systems can significantly reduce the global burden and economic impact of CKD.
Abstract:
The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of the annual healthcare budget in high-income countries. Crucially, however, the onset and progression of CKD is often preventable. In 2020, the World Kidney Day campaign highlights the importance of preventive interventions - be it primary, secondary or tertiary. This complementing article focuses on outlining and analyzing measures that can be implemented in every country to promote and advance CKD prevention. Primary prevention of kidney disease should focus on the modification of risk factors and addressing structural abnormalities of the kidney and urinary tracts, as well as exposure to environmental risk factors and nephrotoxins. In persons with pre-existing kidney disease, secondary prevention, including blood pressure optimization and glycemic control, should be the main goal of education and clinical interventions. In patients with advanced CKD, management of co-morbidities such as uremia and cardiovascular disease is a highly recommended preventative intervention to avoid or delay dialysis or kidney transplantation. Political efforts are needed to proliferate the preventive approach. While national policies and strategies for non-communicable diseases might be present in a country, specific policies directed toward education and awareness about CKD screening, management and treatment are often lacking. Hence, there is an urgent need to increase the awareness of the importance of preventive measures throughout populations, professionals and policy makers.
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