Related Experiment Video
Updated: Dec 18, 2025

07:36
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
11.7K
Global burden of preterm birth
1Global Programs Department, March of Dimes, Arlington, VA, USA.
Summary
Preterm birth, occurring before 37 weeks, affects 11% of births globally and is the leading cause of under-5 mortality. Addressing this critical issue is vital for global child survival goals.
Area of Science:
- Neonatal Health
- Global Public Health
- Obstetrics
Background:
- Preterm birth, defined as birth before 37 completed weeks of gestation, affects approximately 15 million newborns annually worldwide.
- It represents a significant global health challenge, contributing to 18% of all deaths in children under five and 35% of neonatal deaths.
Purpose of the Study:
- To highlight the global burden and impact of preterm birth.
- To underscore its significance in relation to global health objectives, specifically UN Sustainable Development Goal 3.
Main Methods:
- This study is a review of global preterm birth statistics and mortality data.
- Analysis of existing data on preterm birth rates and associated mortality across different income levels and geographical regions.
Main Results:
- The global preterm birth rate stands at approximately 11%, with significant regional disparities.
- Low- and middle-income countries, particularly in Southeast Asia and sub-Saharan Africa, bear a disproportionately high burden.
- Preterm birth rates are increasing in many parts of the world.
Conclusions:
- Preterm birth is a critical determinant of child mortality globally.
- Urgent interventions are needed to reduce preterm birth rates and improve neonatal outcomes, especially in high-burden regions.
- Addressing preterm birth is essential for achieving Sustainable Development Goal 3.2.
Related Concept Videos
Pathophysiology of Diabetes
2.9K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.9K
Teratogenicity
3.8K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
3.8K
Probability Laws
43.7K
Overview
43.7K
Prevalence and Incidence
1.4K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.4K
Diabetes Mellitus: Type 2 and Gestational
4.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.2K
Regression Toward the Mean
6.8K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.8K

