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Published on: August 17, 2022
Living donor liver paired exchange: A North American first
Madhukar S Patel1, Zubaida Mohamed1, Anand Ghanekar1
1Multi Organ Transplant Program, University Health Network, University of Toronto, Toronto, Canada.
Abstract:
Paired organ exchange can be used to circumvent living donor-recipient ABO incompatibilities. Herein, we present the first case of successful liver paired exchange in North America. This 2-way swap required 4 simultaneous operations: 2 living donor hepatectomies and 2 living donor liver transplants. A nondirected anonymous living donor gift initiated this domino exchange, alleviating an ABO incompatibility in the other donor-recipient pair. With careful attention to ethical and logistical issues, paired liver exchange is a feasible option to expand the donor pool for incompatible living liver donor-recipient pairs.
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