SARS-CoV-2-related paediatric inflammatory multisystem syndrome, an epidemiological study, France, 1 March to 17 May

Related Experiment Video

Updated: Dec 18, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.7K

Alexandre Belot1, Denise Antona2, Sylvain Renolleau3

  • 1Filière de santé des maladies auto-immunes et auto-inflammatoires rares (FAI2R), Lyon, France.

Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
|June 12, 2020
PubMed

Insights

Paediatric inflammatory multisystem syndrome (PIMS) cases increased in France during the COVID-19 epidemic. These cases showed a range of symptoms, from Kawasaki-like disease to myocarditis, with many requiring intensive care.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Cardiology

Background:

  • An increase in pediatric inflammatory multisystem syndrome (PIMS) was observed in France in late April 2020.
  • This surge coincided with the coronavirus disease (COVID-19) epidemic.

Purpose of the Study:

  • To investigate the association between PIMS and the COVID-19 epidemic.
  • To characterize the clinical features and outcomes of PIMS cases.

Main Methods:

  • Nationwide surveillance was implemented to identify and track PIMS cases.
  • Cases were classified as confirmed, probable, or possible post-COVID-19 PIMS.

Main Results:

  • 156 cases were reported by May 17, with 108 classified as post-COVID-19 PIMS.
  • Clinical presentations ranged from Kawasaki-like disease to myocarditis.
  • 67% of affected children required intensive care.

Conclusions:

  • A temporospatial association between PIMS and the COVID-19 epidemic was demonstrated.
  • PIMS presents with diverse clinical manifestations in children.
  • Severe illness requiring intensive care is common in PIMS.

Keywords:
COVID-19Kawasaki diseaseSARS-CoV2childreninflammationmyocarditispost-infectious disease

More Related Videos

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic09:03

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic

Published on: November 7, 2020

5.3K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.5K

Related Concept Videos

Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
17.7K
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
414
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
393
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.4K