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Is It Time to Reevaluate the Priority for a West Nile Vaccine?

Alan D T Barrett1

  • 1Department of Pathology and Sealy Institute for Vaccine Sciences, University of Texas Medical Branch, Galveston, Texas, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|June 12, 2020
PubMed
Abstract

No abstract available in PubMed .

Keywords:
West NileWest Nile neuroinvasive diseasevaccine

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Body:In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...
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