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Updated: Dec 18, 2025

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
Published on: May 11, 2016
Circulating tumour cells in head and neck cancers: Biological insights
Vishal Rao1, Gururaj Arakeri1,2, Anand Subash1
1Department of Head and Neck Surgical Oncology & Robotic Surgery, HCG Cancer Hospital, Bengaluru, India.
Abstract:
Tumour metastasis is one of the leading cause of cancer-related mortality. Circulating tumour cells (CTCs) have been implicated in loco-regional and distant metastasis and its role is being extensively studied in various malignancies, including those from the head and neck region. The main challenge in understanding their significance lies in the rarity of these cells in the blood. However, newer technologies have attempted to overcome these pitfalls. This review explores the evolution of CTC research and other related areas, including its biological significance, sustainability within the circulating vascular environment and possible clinical implications.
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